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Karen is 31 years old, 5 feet 3 inches tall, and weighs 190 lbs. Her BMI of 34 is well over the healthy limit, and she has high cholesterol, which puts her at a greater risk for developing coronary artery disease. To keep her cholesterol in check, Karen is following a diet that's lower in fat and cholesterol. Weight loss with XENICAL, along with a nutritionally balanced, reduced-calorie diet can help her further control her cholesterol. This may lower her cardiovascular risk. And, because Karen and her doctor are concerned about her developing diabetes, she'd like to decrease her blood glucose levels too. Results with XENICAL Weight loss with XENICAL plus diet has been shown to significantly lower total and LDL cholesterol ("bad cholesterol") levels and improve the LDL/HDL ratio. Weight loss with XENICAL plus diet also has been shown to reduce insulin levels. Among patients with elevated LDL cholesterol levels, 1 year of treatment with XENICAL plus diet led to a reduction in LDL cholesterol of 9% compared to the effect of diet alone. In addition, LDL/HDL ratios improved by 39% in patients on XENICAL plus diet versus patients on diet alone. In an analysis of over 458 people who were enrolled in three clinical studies, people treated with XENICAL and a reduced-calorie diet were 50% less likely to develop type 2 diabetes or glucose intolerance than people treated with diet alone. The long-term benefits of orlistat on weight-related illnesses and life expectancy have not been studied. *These patients are not real individuals. They are representative patient profiles based on data from clinical studies. |
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